Leonardo Bonucci is out of action for 45-60 days after a serious thigh strain, while Juventus are less prepared to confirm the Dani Alves recovery time.
The pair went off during Sunday’s 3-1 Serie A defeat to Genoa at Marassi.
Bonucci required more in-depth tests, but has now been diagnosed with a lesion to the left femoral bicep.
In its current condition, the injury will require 45-60 days in order to heal, but that could change pending more tests at a later date.
Dani Alves was already diagnosed with a fracture to the left fibula.
No actual recovery time has been given yet, but reports varied between two to four months.
It's a devastating blow to lose Bonucci, as Andrea Barzagli is already out until the New Year with a dislocated shoulder.