Sinisa Mihajlovic returns to face his old club as Milan and Torino go head-to-head for a place in the Coppa Italia quarter-finals.
It kicks off at 20.00 GMT and is a one-off game, to be decided after 90 minutes, extra time or penalties.
The winners go on to face Juventus in the quarter-final on January 25.
Mihajlovic was sacked by President Silvio Berlusconi in April, despite taking the Rossoneri to the Coppa Italia Final last season, where they lost to Juventus under caretaker manager Cristian Brocchi.
Milan won the Supercoppa Italiana in Doha on December 23, beating Juve on penalties following a 1-1 draw.
Alessio Romagnoli and Luca Antonelli are ruled out with flu and muscular problems respectively, while Ignazio Abate is passed fit.
Gianluca Lapadula gets the nod in attack with Suso and Jack Bonaventura, while Jose Ernesto Sosa is given perhaps his final opportunity to impress in midfield.
Torino are without injured Iago Falque, Leandro Castan and Danilo Avelar, so Juan Manuel Iturbe gets his first start after arriving on loan with option to buy from Roma.
Andrea Belotti and Adem Ljajic complete the trident attack in a full-strength Granata line-up, including goalkeeper Joe Hart.
When these sides met in the first round of the season on August 21, Milan ran out 3-2 winners with Gigio Donnarumma saving Belotti’s last-gasp penalty.
Curiously, the two teams meet again in Serie A on Monday evening at the Stadio Grande Torino.
The last time Torino beat Milan, home or away in all competition, was a 1-0 result in Turin on November 4, 2001. It was followed by 11 Rossoneri victories and seven draws.
Milan: Donnarumma; Abate, Gomez, Paletta, De Sciglio; Kucka, Sosa, Bertolacci; Suso, Lapadula, Bonaventura
Milan bench: Storari, Plizzari, Ely, Honda, Poli, Zapata, Vangioni, Cutrone, Bacca, Locatelli, Pasalic, Calabria
Torino: Hart; De Silvestri, Rossettini, Moretti, Barreca; Benassi, Valdifiori, Baselli; Iturbe, Belotti, Ljajic
Torino bench: Padelli, Cucchietti, Carlao, Zappacosta, Lopez, Gustafson, Martinez, Obi, Lukic, Boyè, Ajeti