Atalanta are overflowing with confidence after surging ahead in fourth place and beating Valencia 4-1, but that’s what makes this Sassuolo match so dangerous for them.
Bologna have a shortage of options going into this game, having lost when down to nine men with Genoa, while Udinese seek their first win in five.
Napoli continue to climb the standings under Gennaro Gattuso, but could rest some players against Brescia ahead of the Champions League clash with Barcelona.
Milan are out for precious points and the opportunity to break into the Europa League places, but there are so many other storylines in Florence.
Davide Nicola has asked for ‘consistency’ to keep Genoa in Serie A, whilst Lazio are now genuine Scudetto challengers after beating Inter.
Inter and Sampdoria are both smarting from heavy defeats that badly damaged their standing at either end of the Serie A table.
Roma scraped a victory in the Europa League, but run the very real risk of dropping more Serie A points to a Lecce side that is on a roll.
Leaders Juventus travel to rock bottom SPAL and are expected to rotate the squad ahead of the Champions League clash with Lyon.
Parma are challenging for Europe despite an on-going injury crisis and could inflict further misery on a Torino side in abject crisis.
Two of the biggest surprises in Serie A meet at the Bentegodi on Sunday, but while Hellas Verona keep causing upsets, Cagliari are on a very long slide.