Cagliari have the opportunity to break away definitively from the danger zone with a visit to desperate Benevento.
Roma will be on a high after reaching their first Champions League quarter-finals in a decade, but as Sampdoria learned last week, Crotone will not simply roll over.
Lazio received a huge confidence boost by reaching the Europa League quarter-finals, but could be tired against struggling Bologna.
At Christmas it seemed impossible, a few weeks ago it seemed implausible, but now Milan are very much in the Champions League qualification race.
Napoli look to keep their Scudetto dreams alive as they host Goran Pandev’s Genoa on Sunday.
After being shocked by Crotone a week ago, Sampdoria look to rebound against a determined Inter side in a fight for European places.
Leaders Juventus saw their run of 12 consecutive Serie A victories grind to a halt, as SPAL more than earned their stalemate.
It is a mid-table tussle, as Fiorentina and Torino still eye an unlikely berth in European football next season.
Sassuolo ended their nightmare run and intensified Udinese’s problems with a 2-1 away victory, sealed by Stefano Sensi.
Verona hope to build on their current form and take advantage of Atalanta fatigue to break out of the drop zone.