Paulo Dybala got his second hat-trick of the season, eight goals in four games, to mark his 100th Juventus appearance and conquer Sassuolo 3-1.
The Bianconeri were aiming to maintain their 100 per cent domestic record, but also make up for the midweek 3-0 defeat to Barcelona in the Champions League. Mattia De Sciglio joined Sami Khedira, Claudio Marchisio, Benedikt Howedes and Marko Pjaca on the treatment table, but Giorgio Chiellini, Mario Mandzukic and Juan Cuadrado (who was suspended at Camp Nou) returned. The hosts had to do without star man Domenico Berardi and were looking for their first win of the season.
Sassuolo have won only once in the nine matches against Juventus since being promoted to Serie A, losing seven. The lone draw was 1-1 here in October 2014.
Miralem Pjanic had the first shot on goal within four minutes, stinging Andrea Consigli’s gloves from the edge of the area, then the goalkeeper performed a reaction save on Gonzalo Higuain’s volley, Francesco Acerbi diving in for the block to stop Mandzukic tapping in the rebound.
Stefano Sensi blasted just over the bar from a Claud Adjapong assist, but Dybala broke the deadlock with a moment of magic.
Mandzukic rolled across outside the box and La Joya simply swung his left boot at it, remote-controlling the finish into the far top corner. It was his 50th goal in 100 competitive appearances for Juventus. Dybala also became the first player to score in each of the opening four Serie A games for Juve.
Cuadrado showed Juve confidence was unblemished by the Barcelona beating, as he put in a rabona cross for Mandzukic. When Diego Falcinelli did force a save from Gigi Buffon, he was flagged offside anyway in an extremely tight decision, and smothered the Matteo Politano solo effort.
Pol Lirola, on loan from Juve, put in a sublime cross off the outside of the boot and Chiellini stopped Politano nodding in at the back post.
It was a fairly open game, but Dybala scored his second after the restart, gathering from Cuadrado on the edge of the area only to prod left-footed into the near bottom corner, taking defenders and goalkeeper by surprise in the style of Ronaldinho.
However, moments later Sassuolo got themselves back into the game. Adjapong sprung the offside trap on a long ball with Stephan Lichtsteiner slipping and flicked it past Buffon at the far post, a Daniele Rugani block stopped Falcinelli scoring, but Politano got on the rebound.
Dybala put the dampener on those hopes of a comeback with his second hat-trick of the season, curling a trademark free kick from the D in at the near post.
Douglas Costa rolled across for Cuadrado, but impressive Adjapong made a decisive block.