Juventus routed Lecce 4-0 with all of their goals coming in the second half to move seven points clear at the top of Serie A.
The result also saw Juve record their fifth consecutive clean sheet, their best run for two years, whereas Lecce have now conceded 19 goals in just four games.
The Bianconeri went with Miralem Pjanic, Federico Bernardeschi and Blaise Matuidi at left-back against a Lecce side who were missing five first-teamers, including Diego Farias and Gianluca Lapadula.
Lecce started brightly without creating anything meaningful, although Marco Mancosu did force Wojciech Szczesny into a save from close range.
The Bianconeri did grow into the contest, capitalising on Lucioni’s red card after he was caught in possession and brought down Rodrigo Bentancur as the last man.
Adrien Rabiot’s rocket was pushed away by Gabriel, who was relieved to see Ronaldo send an overhead kick and daisy-cutter wide of his goal.
Ronaldo then spurned a golden opportunity to put the Old Lady ahead, the unmarked No 7 inexplicably heading over the bar from two yards out.
Bernardeschi was guilty of fluffing his lines too, blazing over the Portuguese’s low cross from a similar position moments later.
It seemed the Salentini could hold out like they did in the 1-1 draw between the sides earlier in the season, but Douglas Costa’s introduction clicked Juve into gear.
Although Costa didn’t score, he lit up the Old Lady’s attack as Dybala quickly curled one into the roof of Gabriel’s net for goal No 15 of the season.
Rossettini then tripped Ronaldo, who smashed the resulting penalty past the former Milan goalkeeper.
From that point it was a case of damage limitation for Lecce, who looked like conceding every time the hosts attacked.
Gonzalo Higuain came off the bench for his first appearance since the restart and capped it with Juve’s third goal.
Ronaldo gave up on adding to his tally and became provider, his backheel teeing up the No 9 for an explosive finish.
The league leaders had time for a fourth goal as Matthijs de Ligt went on to scramble home a short corner.
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Sent off: Lucioni 31 (L)