Dries Mertens ended his goal drought after 910 minutes of Serie A football to give Napoli a huge win away to their taboo team Atalanta.
The Benevento revival was cut short in no uncertain terms at the Stadio Dall’Ara, as Blerim Dzemaili made the ideal Bologna comeback.
Franck Kessie’s brace completed a comeback in Cagliari, as Milan overturned the Nicolò Barella opener and both teams ended with 10 men.
Matias Vecino eventually broke through the Alisson Becker blockade to cancel out Stephan El Shaarawy’s opener as Inter and Roma drew 1-1.
Juventus look for their seventh consecutive win in all competition when they host Genoa on Monday evening.
Lazio lost Capocannoniere Ciro Immobile to injury, but still crushed Chievo 5-1 with a Sergej Milinkovic-Savic brace.
Fabio Quagliarella bagged a hat-trick as Sampdoria swept sorry Fiorentina aside at Marassi, ending their positive streak.
Domenico Berardi ended his 10-game goal drought to give Sassuolo a 1-1 draw against revived Torino.
SPAL arguably had the better of this game and were only denied victory by an Alfred Gomis error early on.
Federico Ricci could not have asked for a better debut, as Crotone demolished Hellas Verona in a relegation dogfight.