Duvan Zapata completed the comeback for Atalanta to overturn Andrea Petagna’s SPAL and keep up the Champions League pace.
Mattia Destro ended his year-long goal drought and Danilo hit the bar, but Lukas Lerager’s first strike in Serie A gave Genoa a precious point away to Bologna.
Stephan El Shaarawy, Edin Dzeko and an Aleksandar Kolarov counter-attack allowed a clinical Roma to flatten Chievo, also hitting the woodwork twice.
Goalkeepers Alban Lafont and Alex Meret were the heroes of the hour, as neither Fiorentina nor Napoli could find a way past them.
Lazio moved into the Champions League places with a scrappy 1-0 win against Empoli in Serie A on Thursday.
Lucas Paquetá and Krzysztof Piatek were both on target along with a bizarre own goal, as Milan crushed Cagliari to retain fourth place.
Lautaro Martinez came off the bench and scored with his first touch, as Inter scraped a much-needed victory away to Parma.
Daniel Ciofani gave Frosinone a shock victory away to Sampdoria that drags them closer to safety, as Fabio Quagliarella hit the upright.
Sassuolo were left to rue wasted opportunities, as clinical Juventus emerged 3-0 winners with Sami Khedira, Cristiano Ronaldo and Emre Can.
Ola Aina got the winner for Torino, but Udinese had two goals disallowed, saw a penalty saved and hit the bar in 11 minutes of stoppages.