Diego Milito has asked for patience after the new Inter started the campaign with a 4-3 loss at Palermo.
The Argentine scored twice at the Stadio Barbera, but his side were beaten by a motivated Rosanero in Sicily.
"It's not right to think of the Inter of two years ago," the Argentine international striker, who was part of that treble-winning side, told RAI.
"Today we are a different team, with a new Coach who has other tactics in mind compared to those of the past and we have to be able to adapt to it.
"On a personal level it is always gratifying for a striker to score, but I can't hide my disappointment at the result.
"Naturally we all want to win, but now it's time to look to the future and try to improve."
Gian Piero Gasperini replaced Leonardo on the bench this summer and his 3-4-3 tactics are already under the microscope.
"Of course it's going to take time to adapt to the new formation," he continued. "For us players too.
"For example today an attacking midfielder like Wesley Sneijder played further wide than he usually does.
"I think that he, in particular, has changed position.
"I agree that we have to tighten up in defence especially, but this doesn't only involve defenders."
The Nerazzurri's next League game will be at the weekend when they face Roma at San Siro. The Giallorossi also lost yesterday 2-1 at home to Cagliari.
See the latest Serie A predictions and betting tips with Eurotips.co.uk