Philippe Mexes and Bologna's Gaston Ramirez have been suspended, meaning the Uruguayan will miss the game with Juventus.
The two players were booked during Roma's 1-0 victory at the Dall'Ara last night.
Mexes has only just returned from a two-match ban for insulting officials, but is sidelined again for the match with Parma.
Bologna lose creative figure Ramirez for their crunch tie against Juventus this weekend.
See the latest Serie A predictions and betting tips with Eurotips.co.uk