Milan are without Hakan Calhanoglu, Davide Calabria or Mateo Musacchio against Udinese, while Gianluigi Donnarumma needs a fitness test.
It kicks off on Sunday at 11.30 GMT, click here for a match preview.
Coach Stefano Pioli has won both games between Serie A and the Coppa Italia since switching to a 4-4-2 formation, but is forced into some changes tomorrow.
Watch Serie A live in the UK on Premier Sports for just £11.99 per month including live LaLiga, Eredivisie, Scottish Cup Football and more. Visit: https://subscribe.premiersports.tv/