Leonardo adopts a different approach with Goran Pandev, Houssine Kharja, Samuel Eto'o and Giampaolo Pazzini against Cagliari.
Inter kick off at 19.45 UK time at San Siro and are without the injured Wesley Sneijder, Diego Milito, Lucio, Walter Samuel or suspended Cristian Chivu.
In Sneijder's absence, Leo has chosen a 4-2-3-1 system with Pandev, Kharja and Eto'o supporting Pazzini as the lone centre-forward.
Yuto Nagatomo also starts at left-back, moving Javier Zanetti into midfield with Thiago Motta.
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