Rodrigo De Paul is on the Udinese bench against Milan, fuelling reports of interest from Napoli, Fiorentina and Atletico Madrid.
It kicks off at 17.00 UK time (16.00 GMT), click here for the line-ups and LIVEBLOG.
The Argentina international was sensational last season, with nine goals and eight assists in 36 Serie A appearances.
It earned him a call-up to the Seleccion for the Copa America this summer.
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