Sampdoria host Hellas Verona without suspended Gaston Ramirez and Nicola Murru, while Andrea Bertolacci joins the injury list.
It kicks off on Sunday at 14.00 GMT, click here for a match preview.
Coach Claudio Ranieri has some new issues to deal with, as he already knew that Ramirez and Murru would sit out bans.
Alex Ferrari is a long-term absentee, but midfielder Bertolacci is also unavailable due to a muscular problem.
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