Tammy Abraham will start his first match for Roma this season, replacing the injured Romelu Lukaku in a home Serie A game against Bologna.
It kicks off at 17:30 UK time (GMT+1) at the Stadio Olimpico.
Roma and Bologna are in the race for a Champions League placement alongside Atalanta who beat Monza away on Sunday night.
The Giallorossi beat Milan on Thursday night, qualifying for the Europa League semis for the second year running.
Zeki Celik was sent off after just 29 minutes, so he is expected to start tonight and the same is true of Paulo Dybala who was subbed off against Milan after his teammate was given his marching orders.
Daniele De Rossi is not expected to rotate much, but Lukaku is not available while Evan Ndicka is still resting. Bryan Cristante returns after a one-game ban and Angelino is favourite over Leonardo Spinazzola.
Thiago Motta has a few more doubts. Adama Soumaoro, Lewis Ferguson and Jens Odgaard are injured. Sam Beukema is favourite over Jhon Lucumì in central defence while Alexis Saelemaekers should start as a left winger, leaving Kacper Urbański on the bench.
Roma vs. Bologna – probable line-ups
Roma (4-3-2-1): Svilar; Celik, Mancini, Llorente, Angelino; Cristante, Paredes, Pellegrini; Dybala, Abraham, El Shaarawy.
Bologna (4-1-4-1): Skorupski, Posch, Beukema, Calafiori, Kristiansen; Freuler; Orsolini, Aebischer, Fabbian, Saelemaekers; Zirkzee.