Lorenzo Insigne is expected to start for Napoli with Dries Mertens and Jose Callejon, but there are mixed reports on what tactics and formation Barcelona will use.
The Champions League Round of 16 tie kicks off tonight at Camp Nou, at 20.00 UK time (19.00 GMT).
The first leg ended 1-1 at the Stadio San Paolo back in February, so the Partenopei need to win, or draw by scoring at least two goals.
Napoli’s major question mark is over captain Insigne, who limped off with a groin injury during the final minutes of the 3-1 win over Lazio last week.
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