Mirko Vucinic and Fabio Quagliarella lead the Juventus line against Roma’s Fabio Borini and Pablo Osvaldo, as Francesco Totti is dropped.
The Bianconeri have the opportunity to go three points clear at the top of the table this evening after Milan were held to a 1-1 draw by Bologna.
Antonio Conte has a full squad to choose from and picks a 3-5-2 system to take on Roma.
Vucinic faces his former teammates and admits this is “not a game like the others” for him, while he is partnered by Quagliarella, who has recovered from a thigh problem.
Luis Enrique stages an unexpected revolution in Turin by dropping Totti and Erik Lamela, as they hope to close on the Champions League places.
Nicolas Burdisso, Juan, Marco Cassetti and Bogdan Lobont are out of action.
Borini and Maarten Stekelenburg are carrying knocks, but both of them start, while Daniele De Rossi is re-routed to centre-back.
Juventus: Buffon; Barzagli, Bonucci, Chiellini; Lichtsteiner, Vidal, Pirlo, Marchisio, De Ceglie; Quagliarella, Vucinic
Juventus bench: Storari, Caceres, Pepe, Del Piero, Borriello, Giaccherini, Matri
Roma: Stekelenburg; Rosi, De Rossi, Kjaer, José Angel; Perrotta, Gago, Marquinho; Pjanic; Osvaldo, Borini
Roma bench: Curci, Heinze, Taddei, Greco, Lamela, Bojan, Totti