Mattia Destro returned to Roma training on Wednesday, but Pablo Daniel Osvaldo failed to finish the session.
The summer signing from Siena, via Genoa, underwent an x-ray on Tuesday after picking up a foot problem in the 3-2 loss to Bologna.
Destro was subsequently cleared to resume training which he did earlier today, but there are now concerns over Osvaldo.
The Argentine-born Italian international twisted his left knee while striking the ball which has left him as a doubt for the weekend game at Cagliari.
The former Bologna man will be closely monitored over the next 24 hours.