Juventus begin 2013 against Delio Rossi’s troubled Sampdoria and throw Federico Peluso straight into the starting XI.
The Bianconeri are already Winter Champions and must win to keep Lazio eight points away after last night’s result.
Stephan Lichtsteiner sits out a ban with the injured Giorgio Chiellini, Simone Pepe and Nicklas Bendtner long-term absentees.
Federico Peluso arrived from Atalanta this week and is already in the starting line-up with Simone Padoin and Paul Pogba.
Samp sacked Ciro Ferrara last month to bring in Delio Rossi and hope to turn their dismal season around.
Roberto Soriano is suspended, while Maxi Lopez, Enzo Maresca and Nicola Pozzi are all injured.
Rossi transforms the Blucerchiati to a 3-5-2 system with Angelo Palombo making his comeback in a central defensive role rather than midfield.
Former Juve winger Marcelo Estigarribia also takes to the field with Bianconeri transfer target Pedro Obiang.
Juventus: Buffon; Barzagli, Bonucci, Peluso; Padoin, Pogba, Pirlo, Marchisio, De Ceglie; Matri, Giovinco
Juventus bench: Storari, Branescu, Caceres, Marrone, Isla, Vidal, Giaccherini, Quagliarella, Vucinic
Sampdoria: Romero; Gastaldello, Palombo, Costa; Berardi, Krsticic, Obiang, Poli, Estigarribia; Eder, Icardi
Sampdoria bench: Da Costa, Berni, Castellini, De Silvestri, Mustafi, Poulsen, Rossini, Munari, Renan, Tissone, Savic