The pressure is on Napoli to end their five-match winless streak or risk losing second place, but they welcome an Atalanta side who won here last season.
Not only are the Partenopei now temporarily 12 points adrift of Juventus, but they are only two clear of Milan in third place.
Walter Mazzarri’s men have notched up just four points from the last five games and star striker Edinson Cavani is without a goal in eight official matches.
Miguel Angel Britos is still out after fracturing his jaw, but Paolo Cannavaro returns from suspension.
Goran Pandev is chosen to partner Cavani, leaving Lorenzo Insigne on the bench.
Atalanta welcome back Carlos Carmona from his ban, though Giuseppe De Luca, Ciro Polito and Coach Stefano Colantuono are suspended.
The Orobici won 3-1 at the San Paolo last season, plus beat Napoli in Bergamo back in October, so have a strong recent record.
Maxi Moralez is the support for ex-Napoli striker German Denis.
Napoli: De Sanctis; Campagnaro, Cannavaro, Gamberini; Maggio, Behrami, Dzemaili, Hamsik, Zuniga; Pandev, Cavani
Atalanta: Consigli; Raimondi, Stendardo, Lucchini, Del Grosso; Giorgi, Carmona, Biondini, Bonaventura; Moralez; Denis