Roma need a victory against Parma this evening to keep their European dreams alive and make some surprising changes.
The Giallorossi are in eighth place, while the Ducali are mid-table and almost safe from the drop. Click here for a match preview.
Vasilis Torosidis joined Mattia Destro, Miralem Pjanic and Alessio Romagnoli on the treatment table, but Michael Bradley returns from suspension.
Coach Aurelio Andreazzoli has brought back the three-man defence, while Daniele De Rossi and Panagiotis Tachtsidis start together in midfield.
The big surprise is that Pablo Daniel Osvaldo has been dropped in favour of Erik Lamela and Simone Perrotta supporting lone striker Francesco Totti.
Parma ended their run of just three draws from eight rounds by beating Torino 4-1 last week, but have a terrible record at the Olimpico.
The Ducali are without a victory here since 1997, followed by three points from 15 visits.
They beat Roma 3-2 earlier this season, but went into this game without MacDonald Mariga, Fabiano Santacroce, Andrea Coda, Djamel Mesbah and Raffaele Palladino.
Amauri and Nicola Sansone lead the way, while ex-Roma midfielder Aleandro Rosi is on the wing and 20-year-old Alvaro Ampuero is a surprise pick.
Roma: Stekelenburg; Marquinhos, Burdisso, Castan; Florenzi, De Rossi, Tachtsidis, Marquinho; Lamela, Perrotta; Totti
Roma bench: Goicoechea, Lobont, Dodò, Taddei, Piris, Balzaretti, Bradley, Lucca, Lopez, Osvaldo
Parma: Mirante; Benalouane, Paletta, Lucarelli; Rosi, Parolo, Valdes, Gobbi, Ampuero; Amauri, Sansone
Parma bench: Pavarini, Bajza, MacEachen, Morrone, Biabiany, Galloppa, Belfodil, Strasser, Boniperti, Cerri, Marchionni, Ninis
Betting on Serie A? Bet365 are offering a 100% deposit bonus, up to £200 - find out more