Juventus change system to mirror Carlo Ancelotti’s Real Madrid in the Champions League this evening.
It kicks off at the Bernabeu at 19.45 UK time (18.45 GMT), as the Spaniards defend their 100 per cent record in the competition so far and Juve seek their first win after two draws against Copenhagen and Galatasaray.
Cristiano Ronaldo is supported by Karim Benzema and Angel Di Maria, while Luka Modric gets the nod ahead of Isco.
Gareth Bale is on the bench following a series of thigh and back problems, but Benzema, Fabio Coentrao and Raphael Varane are all back in the squad.
Xabi Alonso is still out of action after breaking his foot, though Ancelotti keeps his promise and returns Iker Casillas to the net.
Juventus have stuttered lately, managing just two draws in the Champions League so far against Copenhagen and Galatasaray, while on Sunday they fumbled a 2-0 lead to lose 4-2 at Fiorentina.
Mirko Vucinic, Fabio Quagliarella and Stephan Lichtsteiner have not made the trip to Madrid, but Antonio Conte has transformed his tactics for this test against his former Juventus Coach Ancelotti.
He shelved the usual 3-5-2 formation for a 4-3-1-2 with Fernando Llorente partnering Carlos Tevez and support from Claudio Marchisio in a more advanced trequartista role.
The big surprises are in defence with Martin Caceres and Angelo Ogbonna stepping in, leaving Leonardo Bonucci and Kwadwo Asamoah on the bench.
It’s a particular risk to start Uruguayan Caceres, who has only played in the Italian Super Cup this season back in August, as he had a knee injury.
Ogbonna hasn’t done much better, featuring in one Champions League game and three Serie A matches.
Juve won their last visit to the Bernabeu, 2-0 in November 2008 thanks to an Alessandro Del Piero brace which earned him a standing ovation.
The Turin giants are unbeaten against Real Madrid since a 1-0 here in February 2005, winning three on the bounce.
Earlier today the youth teams met in the UEFA Youth League, as Real Madrid won 6-2 with Enzo Fernandez on the field, the son of ex-Juve star Zinedine Zidane.
Real Madrid: Casillas; Arbeloa, Ramos, Pepe, Marcelo; Khedira, Illarramendi, Modric; Di Maria, Benzema, Cristiano Ronaldo
Real Madrid bench: Diego López, Varane, Coentrão, Bale, Carvajal, Morata, Isco
Juventus: Buffon; Caceres, Barzagli, Chiellini, Ogbonna; Vidal, Pirlo, Pogba; Marchisio; Tevez, Llorente
Juventus bench: Storari, Isla, Bonucci, Peluso, Padoin, Asamoah, Giovinco