Roma have the opportunity to make history tonight against Chievo, becoming the first Serie A side ever to win the opening 10 games.
It kicks off at the Stadio Olimpico at 19.45 GMT, click here for a match preview.
The Giallorossi have a 100 per cent record so far, equalling the record set by Fabio Capello’s Juventus in 2005-06, but no team has ever maintained that perfect run to the end of Week 10.
Rudi Garcia is without Francesco Totti, Gervinho and the suspended Douglas Maicon, so Adem Ljajic, Marco Borriello and Marquinho form a new trident attack.
Manchester United’s €30m transfer target Miralem Pjanic starts in midfield with Daniele De Rossi and Kevin Strootman.
Vasilis Torosidis and Dodo step in to the full-back roles.
If Roma are flying high, then Chievo are rock bottom, as they are propping up the Serie A table after five consecutive defeats.
Dario Dainelli is in the squad for the first time this season, but Bostjan Cesar sits out a one-match ban.
Cyril Thereau had been expected to start, but picked up a problem in the last training session, so Sergio Pellissier partners Alberto Paloschi. Thereau is not even on the bench.
Roma: De Sanctis; Torosidis, Benatia, Castan, Dodò; Pjanic, De Rossi, Strootman; Ljajic, Borriello, Marquinho
Roma bench: Lobont, Skorupski, Burdisso, Jedvaj, Balzaretti, Romagnoli, Taddei, Florenzi, Bradley, Ricci, Di Mariano, Caprari
Chievo: Puggioni; Frey, Dainelli, Claiton; Sardo, L Rigoni, Hetemaj, Bentivoglio, Drame; Pellissier, Paloschi
Chievo bench: Silvestri, Squizzi, Bernardini, Pamic, Improta, Sestu, Estigarribia, Radovanovic, Papp, Ardemagni, Kupisz, Acosty
Betting on Serie A? Bet365 are offering a 100% deposit bonus, up to £200 - find out more