Alessandro Matri makes his Fiorentina debut from the start against a Catania side with Rolando Maran back in charge.
It kicks off at the Stadio Massimino at 14.00 GMT, click here for a match preview.
There are comebacks all round in Sicily, as Maran is back on the bench less than three months after he was sacked to make way for Gigi De Canio.
Vincenzo Montella was also familiar with the crowd in the stands, having worked as Catania Coach before going to Fiorentina.
It is also the Viola debut for Matri just days after he completed his loan move to Milan, as Giuseppe Rossi and Mario Gomez are on the treatment table for a while yet.
Matri is flanked by Juan Cuadrado and Juan Manuel Vargas, while David Pizarro and Borja Valero complete a quality midfield.
Maran is forced to reshuffle his side, as Francesco Lodi and Gino Peruzzi are suspended with Sergio Almiron and Pablo Alvarez injured.
Curiously, Fiorentina haven’t beaten Catania here since 2008-09.
Catania: Frison; Rolin, Spolli, Bellusci, Biraghi; Izco, Rinaudo, Plasil; Castro, Bergessio, Barrientos
Catania bench: Andujar, Ficara, Legrottaglie, Leto, Lopez, Guarente, Monzon, Boateng, Gyomber, Gontan, Capuano
Fiorentina: Neto; Tomovic, Rodriguez, Savic, Pasqual; Mati Fernandez, Pizarro, Borja Valero; Cuadrado, Matri, Vargas
Fiorentina bench: Rosati, Roncaglia, Compper, Bakic, Rebic, Aquilani, Joaquin, Vecino, Ambrosini, Wolski, Matos Ryder, Ilicic