Sinisa Mihajlovic faces yet another must-win game as Milan visit Frosinone, who have an excellent home record.
The Rossoneri can never seem to find consistency, beating Sampdoria twice between Serie A and the Coppa Italia, but held to draws by minnows Carpi and Verona.
This is a particularly tricky trip because Frosinone earned 13 of their 14 points this season on home turf.
Mario Balotelli has recovered from hip surgery, but is now ruled out by flu, joining Jeremy Menez and Diego Lopez in the stands.
Nigel de Jong and Juraj Kucka are also suspended, but Jack Bonaventura and Andrea Bertolacci shake off injury problems to start.
Keisuke Honda gets a rare start wide right for Milan.
Frosinone have almost a full squad to choose from, missing only Aleandro Rosi.
Frosinone: Leali; M Ciofani, Diakité, Blanchard, Pavlovic; Tonev, Sammarco, Gori, Soddimo; D Ciofani, Dionisi
Frosinone bench: Zappino, Crivello, Russo, Chibsah, Frara, Gucher, Carlini, Castillo, Longo, Paganini, Ajeti, Bertoncini
Milan: Donnarumma; Abate, Alex, Romagnoli, De Sciglio; Honda, Bertolacci, Montolivo, Bonaventura; Niang, Bacca
Milan bench: Abbiati, Livieri, Antonelli, Calabria, Rodrigo Ely, Mexes, Zapata, Josè Mauri, Poli, Cerci, Luiz Adriano