Milan want to continue climbing the table and use Carlos Bacca against Torino striker Ciro Immobile.
It kicks off at 19.45 GMT, follow the build-up and action as it happens on our LIVEBLOG.
The Rossoneri have lost just one of their last 17 competitive games and face Alessandria in the Coppa Italia semi-final on Tuesday night.
They have an extra reason to win big, as they’ll be wearing special jerseys marking the 30th anniversary of President Silvio Berlusconi buying the club.
Riccardo Montolivo is suspended, so Andrea Bertolacci steps into midfield, but the rest remains largely untouched from the side that held Napoli to a 1-1 draw last week.
Bacca parners M’Baye Niang again with Jack Bonaventura and Keisuke Honda out wide.
Alessio Romagnoli missed the Napoli game with flu symptoms and is still feeling debilitated, so remains on the bench.
Torino have Marco Benassi banned and an injury list including Cesare Bovo, Alessandro Gazzi and Danilo Avelar.
Immobile starts up front with Italy Under-21 international Andrea Belotti, while Davide Zappacosta and Bruno Peres can cause problems on the wings.
It’s safe to say the Granata don’t have a good record with Milan. They haven’t beaten them, home or away in all competition, since a 1-0 result in Turin on November 4 2001, followed by nine defeats and seven draws.
The last Serie A victory at San Siro was 1-0 way back on March 24 1985.
Milan: Donnarumma; Abate, Alex, Zapata, Antonelli; Honda, Kucka, Bertolacci, Bonaventura; Niang, Bacca
Milan bench: Abbiati, Livieri, De Sciglio, Mauri, Menez, Romagnoli, Poli, Simic, Balotelli, Boateng, Locatelli, Calabria
Torino: Padelli; Maksimovic, Glik, Moretti; Zappacosta, Acquah, Vives, Baselli, Peres; Belotti, Immobile
Torino bench: Castellazzi, Ichazo, Molinaro, Obi, Farnerud, Maxi Lopez, Martinez, Jansson, Silva