Zlatan Ibrahimovic is in the Milan squad to face Viktoria Plzen, but Massimo Ambrosini has not recovered.
The Rossoneri welcome their Champions League opponents to San Siro on Wednesday at 19.45 UK time.
Ibra has been out of action for several weeks and returned to training yesterday, so has been included in the 20-man squad.
Luca Antonini and Daniele Bonera also return, but Alexandre Pato, Robinho, Kevin-Prince Boateng, Ambrosini, Gennaro Gattuso, Philippe Mexes, Mathieu Flamini and the ineligible Pippo Inzaghi and Stephan El Shaarawy are out.
The striker shortage means Coach Max Allegri has called up youth team player Simone Ganz, the son of club legend Maurizio Ganz.
Milan squad: Abbiati, Amelia, Roma, Abate, Antonini, Bonera, De Sciglio, Nesta, Taiwo, Thiago Silva, Zambrotta, Yepes, Aquilani, Emanuelson, Nocerino, Seedorf, Van Bommel, Cassano, Ibrahimovic, Ganz
Think you know your Italian football? Share your knowledge, tips and comments to win cash prizes in OLBG's tipster competition - £11,000 to be won monthly!