Antonio Cassano and Giuseppe Rossi lead the way with Giorgio Chiellini at left-back as Italy face Serbia tonight.
The Azzurri have already qualified for Euro 2012 by winning the group, but still have two games left to play, welcoming Northern Ireland on Tuesday.
Cesare Prandelli named his starting XI with very few changes despite the fact this match is now irrelevant.
Cassano and Rossi remain the front two with support from Riccardo Montolivo in a trequartista role.
Juventus defender Chiellini moved to left-back at club level last week and is doing the same for the Nazionale, making room for Andrea Barzagli and Leonardo Bonucci.
Prandelli has to do without the injured Domenico Criscito, Federico Balzaretti, Mario Balotelli and Giampaolo Pazzini, who all had to pull out of these qualifiers.
Pablo Daniel Osvaldo received his first senior Italy call-up for this game and is on the bench.
Serbia have a lot to play for, as they are currently in second place and hope to stay there in order to reach the Euro 2012 play-offs.
They will be sure of that spot if they beat Italy this evening, as Slovenia and Estonia are still in the race.
Inter midfielder Dejan Stankovic returns from a long injury lay-off, while Juve winger Milos Krasic and former Lazio star Aleksandar Kolarov are also in the line-up.
Serbia have opted to leave Milan Jovanovic, Radosav Petrovic and Nikola Zigic on the bench in favour of Milos Ninkovic, Ljubomir Fejsa and Marko Pantelic.
Kick-off is at 19.45 UK time at the Stadion FK Crvena Zvezda, commonly referred to as the Marakana.
Serbia: Jorgacevic; Ivanovic, Subotic, Rajkovic, Kolarov; Fejsa, Stankovic; Krasic, Tosic, Ninkovic; Pantelic
Serbia bench: Kahriman, Tomovic, Miljas, Simic, Jovanovic, Petrovic, Zigic
Italy: Buffon; Maggio, Barzagli, Bonucci, Chiellini; De Rossi, Pirlo, Marchisio; Montolivo; Rossi, Cassano
Italy bench: Sirigu, Osvaldo, Aquilani, Cassani, Astori, Giovinco, Nocerino