Juventus look to a trident of Mirko Vucinic, Alessandro Matri and Simone Pepe as they welcome Antonio Conte’s old club Siena.
Conte took the Tuscans to promotion last season before resigning when he received the prestigious call from Turin.
He has a full squad to choose from and opts for the 4-3-3 formation with Vucinic returning from injury.
Paolo De Ceglie is picked at left-back, allowing Giorgio Chiellini to play in central defence.
Siena miss Zeljko Brkic and Francesco Bolzoni for this trip to the Juventus Stadium, but have Mattia Destro as a partner for Emanuele Calaiò.
Juventus: Buffon; Lichtsteiner, Barzagli, Chiellini, De Ceglie; Vidal, Pirlo, Marchisio; Vucinic, Matri, Pepe
Juventus bench: Storari, Bonucci, Giaccherini, Marrone, Del Piero, Quagliarella, Borriello
Siena: Pegolo; Vitiello, Rossettini, Terzi, Del Grosso; Giorgi, Vergassola, Gazzi, Brienza; Destro, Calaiò
Siena bench: Farelli, Rossi, Contini, Parravicini, D’Agostino, Reginaldo, Gonzalez