Milan have Zlatan Ibrahimovic, Robinho and Urby Emanuelson in their trident to take on Lecce at San Siro.
The Rossoneri are currently two points clear at the top of the table and survived a midweek Champions League scare when qualifying despite the 3-0 defeat to Arsenal.
Philippe Mexes continues his three-match ban along with the injured Alexandre Pato, Maxi Lopez, Kevin-Prince Boateng, Alexander Merkel, Rodney Strasser, Clarence Seedorf, Alessandro Nesta, Antonio Cassano and Gennaro Gattuso.
Lecce would be fourth if the season had started at the halfway mark, so are on fine form under Coach Serse Cosmi.
The tactician sits out a touchline ban along with David Di Michele, Nenad Tomovic and Gennaro Delvecchio, joining the injured Carlos Grossmuller, Julio Sergio, Juan Cuadrado and Edward Ofere.
Valeri Bojinov therefore gets a rare start alongside young talent Luis Muriel, while ex-Milan veteran Massimo Oddo returns to San Siro.
Milan: Abbiati; Abate, Bonera, Thiago Silva, Antonini; Nocerino, Van Bommel, Muntari; Emanuelson; Ibrahimovic, Robinho
Lecce: Benassi; Miglionico, Carrozzieri, Esposito, Oddo; Blasi, Giacomazzi, Bertolacci, Brivio; Bojinov, Muriel