Udinese have Antonio Di Natale and Alexis Sanchez to seek Champions League glory against Antonio Cassano's Milan.
The Stadio Friuli is sold out tonight as they need only a point to be sure of fourth place, or can even lose as long as Lazio don't win at Lecce.
Sanchez is back from his recurring ankle injury to start alongside Capocannoniere Di Natale.
Kwadwo Asamoah and Pablo Armero will be particularly eager to impress, as both have been linked with moves to Milan in the summer.
The Rossoneri are resting Zlatan Ibrahimovic due to a slight injury, so Kevin-Prince Boateng returns from suspension to support Alexandre Pato and Cassano.
January signing Didac Vila is given a rare start and it could well be the final game in a Milan shirt for Clarence Seedorf.
Kick-off for all tonight's games is 19.45 UK time.
Udinese: Handanovic; Benatia, Zapata, Domizzi; Isla, Pinzi, Inler, Asamoah, Armero; Sanchez, Di Natale
Milan: Amelia; Abate, Thiago Silva, Yepes, Didac Vilà; Flamini, Van Bommel, Seedorf; Boateng; Pato, Cassano