Mirko Vucinic scored twice in Roma's victory over Sud Tirol, while Novara, Siena and Bologna were also in action.
The Giallorossi saw off Lega Pro side Sud Tirol 3-0 on Saturday evening in their second outing under Luis Enrique.
Marco Borriello opened the scoring after just six minutes with a fierce drive from distance, but Vucinic came alive in the second half.
The want-away striker fought off a defender to net, then completed his brace, both from Francesco Totti assists.
In other friendly news, Novara thrashed Acqui Terme 9-1 in their first match of the season. New signings Pablo Granoche and Takayuki Morimoto both got braces.
Siena also scored nine in their 9-0 win over local team Selezione Fcs thanks to an Emanuele Calaio hat-trick.
Matteo Destro and Gaetano D’Agostino also netted a brace each.
Bologna won a tournament with two mini-matches, beating Molveno 4-0 and Mezzolombardo 3-0.
Marco Di Vaio scored twice in the opening game, while new signing Robert Acquafresca also hit the back of the net.