Lazio have the opportunity to catch Roma in fourth place with a victory, but Ciro Immobile faces his old Torino teammate Andrea Belotti.
It kicks off at the Stadio Olimpico at 20.00 GMT, click here for a match preview.
The Aquile are feeling confident after a dramatic comeback to end Sampdoria’s perfect home record last week, winning 2-1 at Marassi.
With three points this evening, Simone Inzaghi’s men would catch city rivals Roma in fourth place, though both teams have a game in hand.
Luis Nani and Davide Di Gennaro are still out injured, but Felipe Anderson is on the bench after his substitute appearance in the Europa League on Thursday.
That was the Brazilian’s first game of the season due to a series of muscular issues.
Luis Alberto and Lucas Leiva support hitman Immobile, a former Torino player.
He’ll be taking on his Italy partner Belotti, who has been struggling since an ankle sprain kept him out for a month.
M’Baye Niang, Cristian Ansaldi and Umar Sadiq are injured, but Coach Sinisa Mihajlovic (a former Lazio player) makes some surprising changes.
Antonio Barreca, Afriyie Acquah and above all Adem Ljajic are on the bench in favour of Mirko Valdifiori and Alex Berenguer
It’s a family affair at the Olimpico, because Lazio midfielder Sergej Milinkovic-Savic is the brother of Torino second choice goalkeeper Vanja Milinkovic-Savic.
Toro are stalemate specialists, drawing their last four Serie A games.
The Granata haven’t beaten Lazio since a 1-0 home result in December 2013, followed by three draws and five losses.
Their most recent victory at the Olimpico was 2-1 all the way back in November 1993.
Lazio: Strakosha; Bastos, De Vrij, Radu; Marusic, Parolo, Leiva, S Milinkovic-Savic, Lulic; Luis Alberto; Immobile
Lazio bench: Vargic, Guerrieri, Luiz Filipe, Wallace, Cavaco Jordao, Lukaku, Basta, Patric, Murgia, Felipe Anderson, Palombi, Caicedo
Torino: Sirigu; De Silvestri, N'Koulou, Burdisso, Molinaro; Rincon, Valdifiori, Baselli; Iago Falque, Belotti, Berenguer
Torino bench: V Milinkovic-Savic, Ichazo, Acquah, De Luca, Edera, Obi, Barreca, Moretti, Boyè, Fiordaliso, Kone, Lyanco