It’s a dogfight at the Dacia Arena, as Udinese and Sassuolo try to end their dismal runs by going head-to-head.
It kicks off at 17.00 GMT, you’ll be able to follow the action from this game and SPAL-Juventus on the Liveblog.
The Friulani had been transformed under Coach Massimo Oddo, but the honeymoon period is well and truly over after four consecutive defeats.
It’s no coincidence this downturn happened during striker Kevin Lasagna’s injury and he is still out of action along with Gabriele Angella.
Maxi Lopez is supported by Rodrigo De Paul with Seko Fofana getting the midfield nod rather than Ante Balic.
If Udinese are struggling, then Sassuolo are barely staying afloat, as they are winless in nine rounds and have slipped into the relegation zone.
To make matters worse for Coach Beppe Iachini, he has star players Domenico Berardi, Antonino Ragusa and Federico Peluso suspended.
They take drastic action and move to a 3-5-2 formation with Claud Adjapong and Pol Lirola in more advanced roles, Khouma Babacar and Matteo Politano in attack.
Udinese: Bizzarri; Stryger Larsen, Danilo, Samir; Widmer, Fofana, Behrami, Jankto, Adnan; De Paul; Maxi Lopez
Sassuolo: Consigli; Goldaniga, Acerbi, Dell’Orco; Lirola, Mazzitelli, Sensi, Missiroli, Adjapong; Politano, Babacar