The Rome Derby between Roma and Lazio has been moved to an evening kick-off, while Juventus-Sampdoria and Milan-Napoli are also switched.
The Lega Serie A announced the changes to the upcoming fixture list, including the Milan-Inter Derby della Madonnina on April 4 at 17.30 UK time.
Due to Champions League and Europa League commitments, there are also several changes to the Week 32 fixtures for Sunday April 15.
Lazio-Roma had originally been due to kick off at 17.00, but has now been moved to 19.45 UK time.
Milan-Napoli was the evening match, but is now taking place at 14.00 UK time.
Juventus-Sampdoria is also moved from 14.00 to 17.00 UK time.