Join us for all the build-up and action from the Champions League, as Roma visit Real Madrid and Cristiano Ronaldo leads Juventus in Valencia.
They kick off at 20.00 UK time (19.00 GMT).
Inter opened the continental campaign with a comeback to beat Tottenham Hotspur 2-1 last night, while Napoli were held to a goalless draw by Red Star Belgrade.
Juve are widely considered one of the favourites to win the Champions League after reinforcing with Cristiano Ronaldo, Emre Can and the return of Leonardo Bonucci.
They begin by visiting the Mestalla, where Valencia return to the competition after two years out.
Roma reached the semi-final last season, but come face to face with reigning champions Real Madrid at the Bernabeu.
See the latest Serie A predictions and betting tips with Eurotips.co.uk