Cristiano Ronaldo, Mario Mandzukic and Federico Bernardeschi lead Juventus, but Valencia are forced to reshuffle after injuries.
It kicks off at 20.00 UK time (19.00 GMT).
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Cristiano Ronaldo, Mario Mandzukic and Federico Bernardeschi lead Juventus, but Valencia are forced to reshuffle after injuries.
It kicks off at 20.00 UK time (19.00 GMT).
The Bianconeri have made no secret of the fact they are targeting victory in the tournament and invested over €100m in signing Ballon d’Or Cristiano Ronaldo.
He broke his Serie A duck at the weekend with a brace against Sassuolo, but his Champions League record is extraordinary: 120 goals in 153 appearances, including 17 last season.
CR7 leads the line here with support from Mandzukic and Bernardeschi.
There had been reports it would be Douglas Costa, seeing as he received a four-match Serie A ban for spitting at Sassuolo’s Federico Di Francesco and will only be able to play in the Champions League for the next month.
Paulo Dybala is carrying a knock to the foot, with Andrea Barzagli and Mattia De Sciglio also not fully fit.
Despite earlier reports of Juan Cuadrado at right-back, it’s Joao Cancelo with Alex Sandro on the left.
Miralem Pjanic has shaken off his injury concern to start in a very experienced midfield, but Rodrigo Bentancur isn't even on the bench.
Valencia have serious problems putting together a starting XI, because they are forced to do without Francis Coquelin and ex-Inter midfielder Geoffrey Kondogbia.
Ezequiel Garay has been out of action all season and despite struggling with a hamstring issue, former Inter defender Jeison Murillo does start.
Rodrigo is joined in attack by Michy Batshuayi rather than Kevin Gameiro, while Ronaldo’s good friend and fellow Portugal international Goncalo Guedes is on the left flank.
Juventus and Valencia are in the group with Manchester United and Swiss side Young Boys.
Valencia: Neto; Ruben Vezo, Murillo, Gabriel Paulista, Gaya; Soler, Parejo, Wass, Goncalo Guedes; Rodrigo, Batshuayi
Valencia bench: Domenech, Gameiro, Cheryshev, Diakhaby, Torres, Piccini, Santi Mina
Juventus: Szczesny; Cancelo, Bonucci, Chiellini, Alex Sandro; Khedira, Pjanic, Matuidi; Bernardeschi, Mandzukic, Ronaldo
Juventus bench: Perin, Benatia, Rugani, Cuadrado, Can, Dybala, Douglas Costa
Ref: Brych (GER)