Torino use Simone Zaza and Andrea Belotti together, as SPAL rely on Alberto Paloschi and Manuel Lazzari.
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The Granata are brimming with confidence following their narrow victory over Inter.
Koffi Djidji is not fully fit, so Emiliano Moretti steps in to the back three, but Soaliho Meite returns from his two-match ban only for a spot on the bench.
Coach Walter Mazzarri continues the experiment of using Zaza and Belotti together in a 3-5-2 formation.
SPAL finally ended their dismal run of form with a surprise 2-1 victory away to Parma, especially as they had been 1-0 down.
Andrea Petagna is suspended with Francesco Vicari injured, so Paloschi and Mirco Antenucci lead the way with support from Daniele Baselli.
SPAL: Viviano; Bonifazi, Cionek, Felipe, Fares; Lazzari, Valoti, Missiroli, Kurtic; Antenucci, Paloschi
Torino: Sirigu; Izzo, Nkoulou, Moretti; De Silvestri, Lukic, Rincon, Ansaldi, Aina; Belotti, Zaza