Juventus want to maintain their unbeaten Serie A record as they host stuttering Udinese for their 200th game at the Allianz Stadium.
It kicks off at 19.30 GMT and the Bianconeri have the chance to even extend their 16-point lead at the top of the table.
Max Allegri is expected to completely revamp his line-up for this test, as there are only a few days to go before the Champions League showdown with Atletico Madrid.
With that in mind, and the 2-1 win over Napoli last week practically securing an eighth consecutive Scudetto, there is the genuine risk of under-estimating Udinese and allowing an upset.
The Friulani are battling to avoid relegation and are finding some form, winning their last two games.
These two teams haven’t shared the spoils in a Turin-based Serie A fixture since March 1990, followed by 19 home wins and five for the visitors.