Roma have Stephan El Shaarawy and Nicolò Zaniolo supporting Edin Dzeko and Patrik Schick, up against Stefano Okaka and Rodrigo De Paul’s Udinese.
It kicks off at the Stadio Olimpico at 17.00 UK time (16.00 GMT).
You can follow the build-up and action as it happens and give your views on the LIVEBLOG.
Roma have Stephan El Shaarawy and Nicolò Zaniolo supporting Edin Dzeko and Patrik Schick, up against Stefano Okaka and Rodrigo De Paul’s Udinese.
It kicks off at the Stadio Olimpico at 17.00 UK time (16.00 GMT).
You can follow the build-up and action as it happens and give your views on the LIVEBLOG.
The Giallorossi are still very much in the running for a Champions League spot despite their numerous problems this season, which saw Eusebio Di Francesco fired to make way for caretaker manager Claudio Ranieri.
Aleksandar Kolarov is suspended, with Steven Nzonzi, Davide Santon and Rick Karsdorp injured.
Florenzi returns to the squad after almost a month out with a muscular problem, but is not passed fit to start, so Juan Jesus and Ivan Marcano become make-shift full-backs.
Daniele De Rossi starts in midfield with Bryan Cristante, while Zaniolo and El Shaarawy are on the wings of a 4-4-2, with Dzeko and Schick together up top.
Robin Olsen has been definitively benched in favour of Antonio Mirante.
Udinese are feeling more confident too, as they earned a dramatic 3-2 win over Empoli in that relegation dogfight last week, despite seeing Marvin Zeegelaar sent off.
He is therefore suspended, with Bram Nuytinck, Valon Behrami, Antonin Barak and Nicolas Opoku injured.
Stefano Okaka and Kevin Lasagna lead the way with Rodrigo De Paul and Rolando Mandragora in midfield.
Roma: Mirante; Juan Jesus, Manolas, Fazio, Marcano; Zaniolo, De Rossi, Cristante, El Shaarawy; Dzeko, Schick
Udinese: Musso; De Maio, Troost-Ekong, Samir; Stryger-Larsen, Fofana, Mandragora, De Paul, D’Alessandro; Okaka, Lasagna
Ref: Di Bello