Lazio make changes, including a Serie A debut in goal, as they host a Bologna side eager to lock down their Serie A status.
It kicks off at 19.30 UK time (18.30 GMT) at the Stadio Olimpico.
Simone Inzaghi’s men are fresh from Wednesday’s 2-0 Coppa Italia Final victory over Atalanta and will parade the trophy around the pitch this evening.
That result means they have already booked a place in the Europa League group phase and the celebration includes giving 23-year-old goalkeeper Guido Guerrieri his Serie A debut in place of not 100 per cent fit Thomas Strakosha.
Stefan Radu is suspended, with Luis Alberto, Felipe Caicedo, Pedro Neto, Valon Berisha and Jordan Lukaku injured.
Joaquin Correa again supports Ciro Immobile, with Lucas Leiva, Milan Badelj and Marco Parolo in midfield.
Bologna need one point to be sure of their Serie A safety, which is remarkable considering their position when Sinisa Mihajlovic replaced Pippo Inzaghi – Simone’s brother – on the bench.
Federico Mattiello is the only absentee, as Mitchell Dijks, Andrea Poli and Nicola Sansone return from suspension.
They make changes, though, with Mattia Destro leading what appears to be a 4-3-3 formation with Rodrigo Palacio and Riccardo Orsolini in support.
It allows Roberto Soriano to drop into a deeper role.
Lazio: Guerrieri; Bastos, Luiz Felipe, Acerbi; Romulo, Parolo, Leiva, Badelj, Lulic; Correa, Immobile
Bologna: Skorupski; Mbaye, Danilo, Lyanco, Dijks; Poli, Pulgar, Soriano; Orsolini, Destro, Palacio