Milan are expected to stick with the same XI that beat Parma, with Krzysztof Piatek and Giacomo Bonaventura, as they visit Bologna.
It kicks off at the Stadio Dall’Ara at 19.45 GMT, click here for a match preview.
The Rossoneri finally got their first win under Stefano Pioli thanks to a last-gasp Theo Hernandez goal last week.
Mattia Caldara and Leo Duarte are still out of action, while Lucas Paqueta returns to the squad, but is only expected to be on the bench.
Hakan Calhanoglu can therefore remain in midfield with Franck Kessie and Ismael Bennacer, while Bonaventura completes the trident with Suso and Piatek.
Although Rafael Leao was tested in training over the last few days, Piatek is still likely to get the nod upfront.
Bologna have Gary Medel suspended, with Mitchell Dijks and Roberto Soriano on the treatment table.
Mattias Svanberg is in competition with Blerim Dzemaili for a place, while Andreas Skov Olsen is the favourite ahead of Riccardo Orsolini to support Rodrigo Palacio.
Sinisa Mihajlovic is expected to be on the bench for the first time since undergoing a bone marrow transplant.
Bologna (probable): Skorupski; Tomiyasu, Bani, Danilo, Denswil; Poli, Schouten; Skov Olsen, Dzemaili, Sansone; Palacio
Milan (probable): G Donnarumma; Conti, Musacchio, Romagnoli, Theo Hernandez; Kessie, Bennacer, Calhanoglu; Suso, Piatek, Bonaventura
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