Atalanta rely on Papu Gomez, Mario Pasalic and Duvan Zapata in their first Champions League quarter-final, while PSG have Ander Herrera, Neymar and Mauro Icardi.
It kicks off in Lisbon at 20.00 UK time (19.00 GMT).
You can follow all the build-up and action as it happens on the LIVEBLOG.
Atalanta rely on Papu Gomez, Mario Pasalic and Duvan Zapata in their first Champions League quarter-final, while PSG have Ander Herrera, Neymar and Mauro Icardi.
It kicks off in Lisbon at 20.00 UK time (19.00 GMT).
You can follow all the build-up and action as it happens on the LIVEBLOG.
Gian Piero Gasperini’s side have stunned Europe with this run to the Final Eight in their first ever Champions League campaign, especially after losing the first three group stage games.
They crushed Valencia 8-4 on aggregate in the Round of 16 and finished third in Serie A for the second year running.
Josip Ilicic is out of action at the moment due to personal reasons, while Pierluigi Gollini has a knee injury, so Marco Sportiello starts in goal.
Captain Alejandro ‘Papu’ Gomez joins Pasalic and Duvan Zapata upfront, with Ruslan Malinovskyi and Luis Muriel ready to come off the bench in the second half.
PSG have Angel Di Maria suspended, with Layvin Kurzawa and Italy international Marco Verratti injured, but Kylian Mbappé is on the bench for a potential late entry after spraining his ankle.
Edinson Cavani and Thomas Meunier left the club at the end of the Ligue 1 season.
Neymar and ex-Inter hitman Icardi lead the attack with Pablo Sarabia, while Ander Herrera is chosen in midfield to replace Verratti.
Curiously, PSG coach Thomas Tuchel is also injured, having sprained his ankle and fractured the fifth metatarsal in his foot during training last week, so is on crutches.
Paris Saint-Germain have tended to struggle against Italian teams, managing only two wins, seven draws and nine defeats.
Atalanta: Sportiello; Toloi, Caldara, Djimsiti; Hateboer, De Roon, Freuler, Gosens; Gomez, Pasalic; Duvan Zapata
Atalanta bench: Gelmi, Rossi, Sutalo, Palomino, Czyborra, Muriel, Piccoli, Malinovskyi, Da Rica, Castagne, Bellanova, Colley
PSG: Navas; Kehrer, Thiago Silva, Kimpembe, Bernat; Herrera, Marquinhos, Gueye; Neymar, Icardi, Sarabia
PSG bench: Rico, Bulka, Mbappé, Paredes, Choupo-Moting, Diallo, Draxler, Bakker, Kalimuendo-Muinga, Dagba, Ruiz-Atil, Mbe Soh
Ref: Taylor (ENG)