Inter need to beat Shakhtar Donetsk and hope for the best, but the big news is Nicolò Barella starts despite an ankle injury.
It kicks off at 20.00 GMT, you can follow the build-up and action as it happens from this game and Ajax-Atalanta on the LIVEBLOG.
Inter need to beat Shakhtar Donetsk and hope for the best, but the big news is Nicolò Barella starts despite an ankle injury.
It kicks off at 20.00 GMT, you can follow the build-up and action as it happens from this game and Ajax-Atalanta on the LIVEBLOG.
This is the Group of Death, because any of the four teams going into the final game can either reach the Round of 16 or finish bottom and crash out of Europe altogether.
As far as Inter are concerned, they need to win tonight or they will finish in last place.
If they win and Real Madrid-Borussia Monchengladbach ends in a draw, then the Nerazzurri will go third and enter the Europa League.
Arturo Vidal, Radja Nainggolan and Andrea Pinamonti are out of action, but the big doubt to the last moment was around Barella following an ankle injury.
He had treatment to get him in shape and the Italy international has been given the all-clear to start, meaning Christian Eriksen is on the bench yet again.
Lautaro Martinez partners Romelu Lukaku in a 3-5-2 formation, with Achraf Hakimi and Ashley Young on the wings.
Shakhtar Donetsk can not only reach the Round of 16 with a draw, but even have the potential to win the group, as they have a superior head-to-head record with Real Madrid, having beaten the Spaniards home and away.
Inter and Shakhtar drew 0-0 in Ukraine, but the Nerazzurri won 5-0 when these sides met in the Europa League semi-final in August.
Shakhtar also have their injury concerns, with Dentinho and Davit Khocholava carrying knocks, while Junior Moraes, Yevhen Konoplyanka, Ismaily, Viktor Korniienko and Fernando are out of action.
Inter: Handanovic; Skriniar, De Vrij, Bastoni; Hakimi, Gagliardini, Brozovic, Barella, Young; Lautaro Martinez, R Lukaku
Inter bench: Stankovic, Radu, Alexis Sanchez, Kolarov, Sensi, Ranocchia, Perisic, Eriksen, D’Ambrosio, Darmian,
Shakhtar Donetsk: Trubin; Dodô, Bondar, Vitao, Matviyenko; Stepanenko, Kovalenko; Tetê, Marlos, Maycon; Taison
Shakhtar Donetsk bench: Shevchenko, Pyatov, Khocholava, Marcos Antonio, Dentinho, Solomon, Alan Patrick, Marquinhos, Bolbat, V’Yunnik, Sudakov
Ref: Vincic (SVN)