It’s the huge Scudetto showdown, as Juventus welcome Napoli with Carlos Tevez taking on Gonzalo Higuain.
The game kicks off at 19.45 GMT, click here for a match preview.
Roma’s surprise 1-1 draw with Sassuolo today means the winner of this clash will close to within one point of the leaders.
Juventus are on home turf and fresh from a midweek 2-2 Champions League result with Real Madrid.
Giorgio Chiellini, Martin Caceres, Mirko Vucinic, Stephan Lichtsteiner and Simone Pepe are out of action, so Tevez partners Fernando Llorente.
Angelo Ogbonna receives a rare start in defence, having struggled to impress so far this season.
Napoli are coming off a hard-fought 3-2 Champions League victory over Olympique Marseille.
Giandomenico Mesto and Juan Camilo Zuniga are still out of action, while new buy Anthony Reveillere is not yet in the squad.
Pipita Higuain leads the way in Turin supported by Jose Maria Callejon, Marek Hamsik and Lorenzo Insigne.
Juventus: Buffon; Barzagli, Bonucci, Ogbonna; Isla, Vidal, Pirlo, Pogba, Asamoah; Tevez, Llorente
Juventus bench: Storari, Rubinho, De Ceglie, Peluso, Motta, Padoin, Marchisio, Giovinco, Quagliarella
Napoli: Reina; Maggio, Fernandez, Albiol, Armero; Inler, Behrami; Callejon, Hamsik, Insigne; Higuain
Napoli bench: Rafael, Colombo, Cannavaro, Uvini, Britos, Dzemaili, Radosevic, Pandev, Zapata, Mertens