There are fears Kevin Strootman suffered ligament damage after spraining his left knee during Napoli-Roma.
The Dutchman had been in doubt for the game after suffering a knock to his right knee during international duty for Holland against France on Wednesday.
However, in the opening 12 minutes of tonight’s 1-0 defeat at the San Paolo, he fell heavily on to his left knee.
Stretchered off in agony, Roma medical staff confirm he sprained his left knee and more tests will be needed tomorrow to ascertain the damage.
He was seen leaving the Stadio San Paolo using crutches and Coach Rudi Garcia stated his knee was “very swollen.”
It is a particularly heavy blow, as Daniele De Rossi is just one game into his three-round Serie A ban.
See the latest Serie A predictions and betting tips with Eurotips.co.uk