Max Allegri revamps Juventus against Antonio Cassano’s Parma, adopting a Christmas Tree formation.
It kicks off at 14.00 GMT, click here for a match preview.
The Bianconeri are three points clear at the top of the Serie A table and received a huge boost in the Champions League midweek by beating Olympiacos 3-2.
Allegri achieved that with a change of system, starting four at the back for the first time this season and definitively putting the Antonio Conte era behind him.
Now the Bianconeri are embracing the new tactics with a Christmas Tree formation, as Carlos Tevez takes a supporting role with Roberto Pereyra behind Fernando Llorente.
Andrea Pirlo was a late addition to the injury list with Andrea Barzagli, Kwadwo Asamoah, Patrice Evra, Martin Caceres and the suspended Arturo Vidal.
Parma ended a club record run of five consecutive defeats with a surprise 2-0 victory over Inter last week.
What made it even more surprising was that Paolo De Ceglie got both goals, his first ever career brace, and he faces his former club in Turin today.
Cassano leads the line with Abdel Ghezzal, but Jonathan Biabiany, Gabriel Paletta, Marco Cassani, Cristobal Jorquera, Massimo Coda and Bidaoui all miss out.
The Ducali will be wearing special green jerseys that are to be auctioned off after the game to raise funds for people in Parma affected by recent floods.
Juventus: Buffon; Lichtsteiner, Bonucci, Chiellini, Padoin; Romulo, Marchisio, Pogba; Pereyra, Tevez; Llorente
Juventus bench: Storari, Rubinho, Ogbonna, Mattiello, Pepe, Coman, Giovinco, Morata
Parma: Mirante; Felipe, Lucarelli, Costa, Rispoli, Acquah, Lodi, Mauri, De Ceglie; Cassano, Ghezzal
Parma bench: Iacobucci, Belfodil, Lucas Souza, Santacroce, Pozzi, Mariga, Ristovski, Palladino, Gobbi, Galloppa, Coric, Pedro Mendes