Inter included Joao Miranda in the squad to face Milan, pending tomorrow’s fitness test.
It kicks off on Sunday at 19.45 UK time (18.45 GMT), click here for a match preview.
Miranda returned from international duty with an injury, but Coach Roberto Mancini is adamant he could recover in time to start.
If not, Gary Medel or Andrea Ranocchia will take over at centre-back.
Mauro Icardi is available after a muscular problem in the opening game against Atalanta.
Deadline day signings Felipe Melo, Alex Telles, Ivan Perisic and Adem Ljajic are all included and could make their Inter debuts in the Derby della Madonnina.
Inter squad for Milan: Handanovic, Carrizo, Berni; Juan Jesus, Telles, Montoya, Santon, Ranocchia, Murillo, Miranda, D'Ambrosio, Nagatomo; Kondogbia, Guarin, Medel, Gnoukouri, Brozovic, Felipe Melo; Palacio, Icardi, Jovetic, Biabiany, Ljajic, Perisic, Manaj
Watch Serie A live in the UK on Premier Sports for just £9.99 per month including live LaLiga, Eredivisie, Scottish Cup Football and more. Visit: https://www.premiersports.com/subscribenow