Antonio Conte plans eight or nine changes to the Italy line-up against the Republic of Ireland, as they already top Group E.
The Azzurri won their opening two games against Belgium and Sweden, so are guaranteed top spot regardless of Wednesday’s result.
Antonio Candreva is carrying an injury and Gigi Buffon is resting after suffering from flu symptoms, so those are two certain absentees.
According to the latest reports, there will be either eight or nine changes to the line-up.
PSG goalkeeper Salvatore Sirigu will get to play in France, while Angelo Ogbonna and Matteo Darmian step in for Leonardo Bonucci and Giorgio Chiellini.
Only Andrea Barzagli is expected to remain from the usual three at the back, as he is not on a yellow card.
Stephan El Sharawy and Mattia De Sciglio are the favourites to take the wings, so no room for Federico Bernardeschi or Lorenzo Insigne.
In midfield Thiago Motta pulls the strings with Stefano Sturaro and Alessandro Florenzi.
The strike partnership should be Ciro Immobile and Simone Zaza.
With these players, De Sciglio could go deeper to create a 4-4-2 if needed.
Italy already know they will play their Round of 16 tie in Paris on June 27.
Italy (probable): Sirigu; Barzagli, Ogbonna, Darmian; De Sciglio, Florenzi, Thiago Motta, Sturaro, El Shaarawy; Immobile, Zaza