Luis Enrique changes Roma again for tonight's meeting with Siena, as Marco Borriello starts with Simone Perrotta confirmed at right-back.
The Spanish Coach has repeatedly tinkered with his formation and is still looking for his first competitive victory in charge of the club.
Pablo Daniel Osvaldo and Francesco Totti remain from the 0-0 draw with Inter, but Borriello pushes into the starting XI in place of Fabio Borini.
In defence Jose Angel returns from suspension, replacing Rodrigo Taddei, but Perrotta continues the experiment of playing right-back.
Bogdan Lobont takes over in goal, preferred to Gianluca Curci after Maarten Stekelenburg was knocked unconscious in a collision with Lucio last week. Stekelenburg joins Erik Lamela and Juan on the treatment table.
Siena are also looking for their first win of the season and indeed their first goal, having drawn at Catania and lost 1-0 to Juventus.
Franco Brienza is again supporting Emanuele Calaiò with Gabriele Angella the only injury case.
Roma: 1 Lobont; 20 Perrotta, 44 Kjaer, 29 Burdisso, 3 Jose' Angel; 15 Pjanic, 16 De Rossi, 7 Pizarro; 22 Borriello, 10 Totti, 9 Osvaldo
Roma bench: 18 Curci, 5 Heinze, 87 Rosi, 19 Gago, 2 Cicinho, 31 Borini, 14 Bojan
Siena: 1 Brkic; 2 Vitiello, 26 Pesoli, 80 Contini, 3 Del Grosso; 6 Angelo, 14 Gazzi, 8 Vergassola, 17 Grossi; 23 Brienza, 11 Calaiò
Siena bench: 25 Pegolo, 19 Terzi, 21 Rossi, 36 Bolzoni, 10 D'Agostino, 22 Destro, 63 Larrondo
See the latest Serie A predictions and betting tips with Eurotips.co.uk