Inter give Marko Arnautovic and Marcus Thuram an opportunity for tonight’s trip to relegation-threatened Frosinone, as Matias Soule and Walid Cheddira lead the attack.
It kicks off at the sold-out Stadio Stirpe at 19.45 UK time (18.45 GMT).
You can follow all the build-up and action as it happens on the LIVEBLOG.
The Nerazzurri already won the Scudetto and had their celebration parade, but showed hangover symptoms when losing 1-0 to struggling Sassuolo.
Simone Inzaghi is eager to avoid a similar situation, but still rotates the squad with Lautaro Martinez rested and Francesco Acerbi injured.
Thuram therefore partners Arnautovic, with Nicolò Barella and Federico Dimarco returning to the side.
Frosinone are two points clear of the relegation zone and coach Eusebio Di Francesco is forced into changes, as Enzo Barrenechea is suspended, with Stefano Turati, Simone Romagnoli, Mateus Lusuardi, Anthony Oyono and Sergio Kalaj injured.
Their star man is Juventus-owned Matias Soule, who has 11 goals and three assists in Serie A this season, but he scored only one in his last 11 games.
The Canarini have lost all five previous Serie A meetings with Inter, scoring one goal and conceding 13.
Frosinone vs. Inter line-ups
Frosinone: Cerofolini; Lirola, Okoli, Bonifazi; Zortea, Mazzitelli, Reinier, Valeri; Brescianini, Soulé; Cheddira
Inter: Sommer; Bisseck, De Vrij, Carlos Augusto; Darmian, Frattesi, Asllani, Barella, Dimarco; Thuram, Arnautovic
